Single Cell Analysis
- Pretschner, A., Pabel, S., Haas, M., Heiner, M., Marwan, W. 2021. Regulatory Dynamics of Cell Differentiation Revealed by True Time Series From Multinucleate Single Cells. Frontiers in Genetics, Systems Biology.
- Rätzel, V., Werthmann, B., Haas, M., Strube, J. and Marwan, W. 2020. Disentangling a Complex Response in Cell Reprogramming and Probing the Waddington Landscape by Automatic Construction of Petri Nets. Biosystems 189, Elsevier https://doi.org/10.1016/j.biosystems.2019.104092
- Glöckner, G., Marwan, W. 2017. Transcriptome reprogramming during developmental switching in Physarum polycephalum involves extensive remodeling of intracellular signaling networks. Scientific Reports 7: 12304.
- Werthmann, B. and Marwan, W. 2017. Developmental switching in Physarum polycephalum: Petri net analysis of single cell trajectories of gene expression indicates responsiveness and genetic plasticity of the Waddington quasipotential landscape. J. Phys. D: Appl. Phys. 50 (2017) 464003 (18pp)
- Schaap, P. et al. 2016. The Physarum polycephalum genome reveals extensive use of prokaryotic two-component and metazoan-type tyrosine kinase signaling. Genome Biology and Evolution 8: 109-125.
- Rätzel, V., Marwan, W. 2015. Gene expression kinetics in individual plasmodial cells reveal alternative programs of differential regulation during commitment and differentiation. Develop Growth Differ 57, 408-420.
- Walter, P., Hoffmann, X.-K., Ebeling, B., Haas, M. and Marwan, W. 2013. Switch-like reprogramming of gene expression after fusion of multinucleate plasmodial cells of two Physarum polycephalum sporulation mutants. Biochemical and Biophysical Research Communications 435-1, 88 - 93
- Rätzel, V., Ebeling, B., Hoffman, X., Tesmer, J. and Marwan, W. 2013. Physarum polycephalum mutants in the photocontrol of sporulation display altered patterns in the correlated expression of developmentally regulated genes. Development, Growth & Differentiation 55 (2), 247 - 259
- Barrantes I., Leipzig, J. and Marwan, W. 2012. A next-generation sequencing approach to study the transcriptomic changes during the differentiation of Physarum at the single-cell level Gene Regulation and Systems Biology 2012:6, 127 - 137
- Hoffmann, X., Tesmer, J., Souquet, M. and Marwan, W. 2012. Futile attempts to differentiate provide molecular evidence for individual differences within a population of cells during cellular reprogramming. FEMS Microbiology Letters, Online First, 15 February 2012.
- Barrantes, I., Glöckner, G., Meyer, S. and Marwan, W. 2010. Transcriptomic changes arising during light-induced sporulation in Physarum polycephalum. BMC Genomics 11, 115.
- Glöckner, G., Golderer, G. Werner-Felmayer, G., Meyer, S. and Marwan, W. 2008. A first glimpse at the transcriptome of Physarum polycephalum. BMC Genomics 9, 6.
- Sujatha, A., Balaji, S., Devi, R. and Marwan, W. 2005. Isolation of Physarum polycephalum plasmodial mutants altered in sporulation by chemical mutagenesis of flagellates. European Journal of Protistology 41, 19-27.
- Materna, S., and Marwan, W. 2005. Estimating the number of plasmids taken up by a eukaryotic cell during transfection and evidence that antisense RNA abolishes gene expression in Physarum polycephalum. FEMS Microbiology Letters 243, 29-35.
- Marwan W., Sujatha, A. and Starostzik, C. 2005. Reconstructing the regulatory network controling commitment and sporulation in Physarum polycephalum based on hierarchical Petri net modeling and simulation. Journal of Theoretical Biology 236, 349-365.
- Marwan, W. 2003. Theory of time-resolved somatic complementation and its use for the analysis of the sporulation control network of Physarum polycephalum. Genetics 164, 105-115.
- Marwan, W., and Starostzik, C. 2002. The sequence of regulatory events in the sporulation control network of Physarum polycephalum analysed by time-resolved somatic complementation of mutants. Protist 153, 391-400.
- Lamparter, T., and Marwan, W. 2001. Spectroscopic detection of a phytochrome-like photoreceptor in the Myxomycete Physarum polycephalum and the kinetic mechanism for the photocontrol of sporulation by Pfr. Photochemistry and Photobiology 73, 697-702.
- Kroneder, R., Cashmore, A. R. and Marwan, W. 1999. Phytochrome-induced expression of lig1, a homologue of the fission yeast cell cycle checkpoint gene hus1 is associated with the developmental switch in Physarum polycephalum plasmodia. Currrent Genetics 36, 86-93.
- Starostzik, C., and Marwan, W. 1998. Kinetic analysis of a signal transduction pathway by time-resolved somatic complementation of mutants. Journal of Experimental Biology 201, 1991-1999.
- Starostzik, C., and Marwan, W. 1995. Functional mapping of the branched signal transduction pathway that controls sporulation in Physarum polycephalum. Photochemistry and Photobiology 62, 930-933.
- Starostzik, C., and Marwan, W. 1995. A photoreceptor with characteristics of phytochrome triggers sporulation in the true slime mould Physarum polycephalum. FEBS Letters 370, 146-148.
- Starostzik, C., and Marwan, W. 1994. Time-resolved detection of three intracellular signals controlling photomorphogenesis in Physarum polycephalum. Journal of Bacteriology 176, 5541-5543.